The study evaluated the human capital development strategies and performance of pharmaceutical firms in Enugu State, Nigeria. The specific objectives of the study were to; examine the relationship between employee training and output and identify the relationship between coaching and quality of products of pharmaceutical firms in Enugu State, Nigeria.  The target population of the study consists of three hundred and forty-one (341) senior and junior staff of the firms understudy.  The whole population was used due to small number. The study used the descriptive survey design approach. The primary sources of data were the administration of questionnaire.  253 staff returned the questionnaire and accurately filled. Data was presented and analyzed by mean score and Pearson correlation (r) were used to test the hypotheses. The results showed that Employee training had significant positive relationship with the output (r = .466 < .775, p<.05). And that coaching had significant positive relationship with the quality of products (r = .494 < .737, p<.05).  The study concluded that employee training and coaching had significant positive relationship with output, quality of products, sales volume and revenue generation of pharmaceutical manufacturing firms in Enugu State. The study recommended among others that Organizations should organize trainings for new employees and as well sponsor and encourage employees to attend seminars and conferences that will enhance their knowledge and increase their proficiency.